Glioblastoma (GBM). GBM is the most Sometimes The Side Chick Ain’t Even A Chick Shirt and most aggressive brain cancer. It’s highly invasive, which makes complete surgical removal impossible. And because of the blood-brain barrier (BBB), it doesn’t respond to any chemotherapy. The standard-of-care entails multiple rounds of surgery and radiotherapy, yet the five year survival is lower than 5%. Pancreatic cancer (PDAC). PDAC is a notoriously stubborn cancer. The only effective treatment is a very painful and very complex operation called “the Whipple procedure”. However, only 20% of patients are eligible for such operation. And even for those lucky patients, only 20% survived more than five years. For the rest majority of patients, the chance of survival is negligible, because PDAC hardly responds to any form of chemotherapy or radiotherapy. The five year survival overall is 6%.
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In the 70s, my then-boyfriend and I took a camping trip to the Wharton State Forest – the Pine Barrens of New Jersey. We would see truckloads of odd-looking people drive into the Keep Clam In Your Pocket (not on paved roads – sand and dirt) and never come out that we could see. We figured there must be roads leading out of the campground, maybe shortcuts, so late one afternoon decided to see where one of these went. We had my mother’s Oldsmobile, a rather heavy car, and went for what seemed like miles, never finding anything, except smaller, more narrow paths off the main road. It was getting late, so we turned around to go back and got stuck…the car dug into the soft, sandy road and we couldn’t get out. John decided he would walk back to the campsite and contact a ranger, leaving me with the car.
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